Drugs: Trump May Propose MFN; PBMs Using Various Ways To Control GLP-1 Costs
Politico reports exclusively that Donald Trump is on the verge of proposing most-favored nation (MFN) pricing, the strictest form of international reference pricing, to lower drug costs. The executive order would cover the Medicare program for now, but recently the president urged MFN for Medicaid as well. The move would be a major confrontation with the brand drug industry. I have argued Trump’s populism would win out here and he would propose something like this. My blog on the topic: https://www.healthcarelabyrinth.com/expect-big-things-from-donald-trump-on-drug-prices/ .
In other news, pharmacy benefits managers (PBMs) are using various and disparate ways to reduce GLP-1 weight-loss drug trends. CVS has dropped Zepbound in favor of Wegovy in the commercial world. It is also using NovoCare, Novo Nordisk’s direct-to-consumer platform for GLP-1s. Humana will also use NovoCare.
In 2024, Cigna launched EncircleRx, a program that controls the cost of GLP-1 medications for employers. The program has grown to 9 million enrollees in a year.
Given high costs, many employers are dropping coverage for weight loss.
Additionally, The Wall Street Journal attacked Donald Trump for proposing drug price reforms. Of course, Trump is right on this one and I have written about it. What was once a great editorial page, The WSJ has increasingly abandoned their economic principles in favor of shilling for big business no matter what. What the Journal misses is that the drug market is not a free market and reforms need to occur.
As well, Health Affairs Forefront has a blog detailing the so-called small molecule drug “pill penalty.” Trump wants to make a concession here by perhaps moving the Medicare drug price negotiation period out four years for these drugs to match other drugs. The authors argue there will be major lost savings. Perhaps some drugs should be reduced by two years and small molecules moved out two years. That would throw Big Pharma even more.
Additional articles: https://www.beckerspayer.com/payer/payers-split-on-glp-1-strategy/ and https://thehill.com/homenews/media/5289600-wall-street-journal-donald-trump-executive-order-drug-prices/ and https://www.healthaffairs.org/content/forefront/costs-extending-small-molecule-exemption-period-medicare-drug-price-negotiation
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https://www.politico.com/news/2025/05/07/trump-sweeping-medicare-drug-price-plan-00334167